Spheroids and Organoids: Advancing 3D Cell Culture for More Physiologically Rele
2026-07-20
For decades, two-dimensional cell culture has been a fundamental tool in biological and biomedical research. However, cells in the body do not grow as flat monolayers: they interact with neighbouring cells, extracellular matrix components, soluble factors, oxygen gradients and mechanical cues within a three-dimensional microenvironment. For this reason, increasingly advanced in vitro models are moving beyond traditional 2D systems toward 3D cell culture approaches based on spheroids and organoids.
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